Safrole oil is carcinogenic in rats and banned because of the FDA [one]. Despite the warning, sassafras root continues to be normally eaten for its special taste and by those trying to find its gentle psychoactive effects.
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These ways are needed for any drug trials on humans, but investigation involving Program I medication have added requirements throughout the Drug Enforcement Administration.
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Small quantities of sassafras are in tea sections and overall health food items stores. Some merchandise should have the safrole removed.